Protective Efficacy of Plasmodium vivax Radiation-Attenuated Sporozoites in Colombian Volunteers: A Randomized Controlled Trial.

• প্রধান লেখক: Myriam Arévalo-Herrera (লেখক), Juan M Vásquez-Jiménez (লেখক), Mary Lopez-Perez (লেখক), Andrés F Vallejo (লেখক), Andrés B Amado-Garavito (লেখক), Nora Céspedes (লেখক), Angélica Castellanos (লেখক), Karen Molina (লেখক), Johanna Trejos (লেখক), José Oñate (লেখক), Judith E Epstein (লেখক), Thomas L Richie (লেখক), Sócrates Herrera (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Public Library of Science (PLoS), 2016-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Immunizing human volunteers by mosquito bite with radiation-attenuated Plasmodium falciparum sporozoites (RAS) results in high-level protection against infection. Only two volunteers have been similarly immunized with P. vivax (Pv) RAS, and both were protected. A phase 2 controlled clinical trial wa...