Effects of caffeine, tea polyphenol and daidzein on the pharmacokinetics of lansoprazole and its metabolites in rats

• Main Authors: Tao Wu (Author), Ji Wu (Author), Ping Gao (Author), Daochun Xiang (Author), Dong Liu (Author), Hongping Song (Author)
• Format: Book
• Published: Universidade de São Paulo, 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

abstract The aim of this study was to evaluate the effects of caffeine, tea polyphenol and daidzein on the pharmacokinetics of lansoprazole and its metabolites. Rats were intragastrically administered caffeine (30 mg·kg-1, once per day), tea polyphenol (400 mg·kg-1, once per day) or daidzein (13.5 m...