Disruption of androgen signaling during puberty affects Notch pathway in rat seminiferous epithelium

• Main Authors: Alicja Kamińska (Author), Sylwia Marek (Author), Laura Pardyak (Author), Małgorzata Brzoskwinia (Author), Piotr Pawlicki (Author), Barbara Bilińska (Author), Anna Hejmej (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Onset of spermatogenesis at puberty is critically dependent on the activity of hypothalamic-pituitary-gonadal axis and testosterone production by Leydig cells. The aim of this study was to examine whether activation of Notch receptors and expression of Notch ligands and effector...