Copy number variation profiling in pharmacogenetics CYP-450 and GST genes in Colombian population

• Main Authors: Brian Ramírez (Author), María José Niño-Orrego (Author), Daniel Cárdenas (Author), Kevin Enrique Ariza (Author), Karol Quintero (Author), Nora Constanza Contreras Bravo (Author), Caroll Tamayo-Agudelo (Author), María Alejandra González (Author), Paul Laissue (Author), Dora Janeth Fonseca Mendoza (Author)
• Format: Book
• Published: BMC, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Copy Number variation (CNVs) in genes related to drug absorption, distribution, metabolism and excretion (ADME) are relevant in the interindividual variability of drug response. Studies of the CNVs in ADME genes in Latin America population are lacking. The objective of the study...