IL-10 Dampens the Th1 and Tc Activation through Modulating DC Functions in BCG Vaccination

• Main Authors: Hui Xu (Author), Yanjuan Jia (Author), Yonghong Li (Author), Chaojun Wei (Author), Wanxia Wang (Author), Rui Guo (Author), Jing Jia (Author), Yu Wu (Author), Zhenhao Li (Author), Zhenhong Wei (Author), Xiaoming Qi (Author), Yuanting Li (Author), Xiaoling Gao (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BCG, the only registered vaccine against Mycobacterial Tuberculosis (TB) infection, has been questioned for its protective efficacy for decades. Although lots of efforts were made to improve the BCG antigenicity, few studies were devoted to understand the role of host factors in the variability of t...