Dapagliflozin Mediates Plin5/PPARα Signaling Axis to Attenuate Cardiac Hypertrophy

Objective: The purpose of this study was to investigate the effect of dapagliflozin (DAPA), a sodium-glucose cotransporter 2 inhibitor, on relieving cardiac hypertrophy and its potential molecular mechanism.Methods: Cardiac hypertrophy induced by abdominal aortic constriction (AAC) in mice, dapaglif...

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Main Authors: Jing Yu (Author), Huanhuan Zhao (Author), Xin Qi (Author), Liping Wei (Author), Zihao Li (Author), Chunpeng Li (Author), Xiaoying Zhang (Author), Hao Wu (Author)
Format: Book
Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
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