Liposomal Bupivacaine (Bupigel) Demonstrates Minimal Local Nerve Toxicity in a Rabbit Functional Model

• المؤلفون الرئيسيون: Yaelle Bavli (مؤلف), Malcolm Rabie (مؤلف), Yakov Fellig (مؤلف), Yoram Nevo (مؤلف), Yechezkel Barenholz (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2021-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

We previously reported the development of a novel formulation of an ultra-long-acting local anesthetic based on bupivacaine encapsulated in large multivesicular liposomes (Bupisomes) embedded in hydrogel. This formulation (Bupigel) prolonged bupivacaine release from the formulation in dissolution-li...