Diagnostic yield and variant reassessment in the genes encoding Nav1.5 channel in Russian patients with Brugada syndrome

• Κύριοι συγγραφείς: Elena Zaklyazminskaya (Συγγραφέας), Anna Shestak (Συγγραφέας), Dmitry Podolyak (Συγγραφέας), Vera Komoliatova (Συγγραφέας), Leonid Makarov (Συγγραφέας), Anna Novitskaya (Συγγραφέας), Amiran Revishvili (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Brugada syndrome (BrS) is an inherited cardiac arrhythmia characterized by ST-elevation, negative T-wave, and a high risk of sudden cardiac death (SCD) due to ventricular tachycardia. It is associated with mutations in over 20 genes but only SCN5A is recommended for routine genetic screening. This s...