Simultaneous suppression of PKM2 and PHGDH elicits synergistic anti-cancer effect in NSCLC
Metabolic reprogramming is a hallmark of human cancer. Cancer cells exhibit enhanced glycolysis, which allows glycolytic intermediates to be diverted into several other biosynthetic pathways, such as serine synthesis. Here, we explored the anti-cancer effects of the pyruvate kinase (PK) M2 inhibitor...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Frontiers Media S.A.,
2023-05-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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