Rare homozygous mutation in TUBB8 associated with oocyte maturation defect-2 in a consanguineous mating family

• Main Authors: Qiong Xing (Author), Ruyi Wang (Author), Beili Chen (Author), Lin Li (Author), Hong Pan (Author), Tengyan Li (Author), Xu Ma (Author), Yunxia Cao (Author), Binbin Wang (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Purpose Variations in many genes may lead to the occurrence of oocyte maturation defects. To investigate the genetic basis of oocyte maturation defects, we performed clinical and genetic analysis of a pedigree. Methods The proband with oocyte maturation defect-2 receiving ovulation inductio...