Real-time whole-genome sequencing surveillance for outbreak detection and intervention

• Main Authors: Alexander Sundermann (Author), Marissa Griffith (Author), Vatsala Rangachar Srinivasa (Author), Kady Waggle (Author), Jane Marsh (Author), Daria Van Tyne (Author), Ashley Ayres (Author), Lora Pless (Author), Graham Snyder (Author), Lee Harrison (Author)
• Format: Book
• Published: Cambridge University Press, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Detecting healthcare-associated transmission and outbreaks often relies on reactive whole-genome sequencing (WGS), which occurs after the suspected transmission has occurred. Additionally, reactive WGS frequently misidentifies transmission and misses transmission when it has occurred. We...