IL-6 production through repression of UBASH3A gene via epigenetic dysregulation of super-enhancer in CD4+ T cells in rheumatoid arthritis
Abstract Background Rheumatoid arthritis (RA) is associated with immune dysfunction. UBASH3A as a negative regulator of T cell receptors (TCRs) signaling is a susceptible factor in RA. The aim of this study was to determine the role of UBASH3A in RA pathogenesis, by assessing the role of super-enhan...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2022-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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