Formation of CSE-YAP complex drives FOXD3-mediated transition of neurotoxic astrocytes in Parkinson's disease

• Glavni autori: Rong-Xin Zhu (Autor), Yue-Han Chen (Autor), Xian Xia (Autor), Ting Liu (Autor), Cong Wang (Autor), Lei Cao (Autor), Yang Liu (Autor), Ming Lu (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2024-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Astrocytes, constituting the predominant glial cells in the brain, undergo significant morphological and functional transformations amidst the progression of Parkinson's disease (PD). A majority of these reactive astrocytes display a neurotoxic phenotype, intensifying inflammatory responses. No...