Formation of CSE-YAP complex drives FOXD3-mediated transition of neurotoxic astrocytes in Parkinson's disease

• Príomhchruthaitheoirí: Rong-Xin Zhu (Údar), Yue-Han Chen (Údar), Xian Xia (Údar), Ting Liu (Údar), Cong Wang (Údar), Lei Cao (Údar), Yang Liu (Údar), Ming Lu (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Elsevier, 2024-12-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Astrocytes, constituting the predominant glial cells in the brain, undergo significant morphological and functional transformations amidst the progression of Parkinson's disease (PD). A majority of these reactive astrocytes display a neurotoxic phenotype, intensifying inflammatory responses. No...