Formation of CSE-YAP complex drives FOXD3-mediated transition of neurotoxic astrocytes in Parkinson's disease

• Main Authors: Rong-Xin Zhu (Author), Yue-Han Chen (Author), Xian Xia (Author), Ting Liu (Author), Cong Wang (Author), Lei Cao (Author), Yang Liu (Author), Ming Lu (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Astrocytes, constituting the predominant glial cells in the brain, undergo significant morphological and functional transformations amidst the progression of Parkinson's disease (PD). A majority of these reactive astrocytes display a neurotoxic phenotype, intensifying inflammatory responses. No...