Mantonico and Pecorello Grape Seed Extracts: Chemical Characterization and Evaluation of <i>In Vitro</i> Wound-Healing and Anti-Inflammatory Activities
The winemaking process produces a huge number of pomaces that generally are used for energy purposes. Further valuable applications such as health-promoting properties are still under investigation. The seeds of the white berries of Mantonico and Pecorello <i>cv.</i> were extracted in a...
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| Main Authors: | , , , , , , , , , |
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| Format: | Book |
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MDPI AG,
2020-05-01T00:00:00Z.
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| Summary: | The winemaking process produces a huge number of pomaces that generally are used for energy purposes. Further valuable applications such as health-promoting properties are still under investigation. The seeds of the white berries of Mantonico and Pecorello <i>cv.</i> were extracted in a Soxhlet apparatus, using <i>n</i>-hexane and chloroform as solvents. Extracts were characterized by NMR and GC-MS analyses. They were assayed in vitro as wound healing and anti-inflammatory agents in HaCaT and RAW 264.7 cell lines, respectively. <i>n</i>-hexane Mantonico extract resulted in the most interesting wound healing sample, while <i>n</i>-hexane Pecorello, containing a good number of carotenoids, resulted in a good anti-inflammatory candidate. These preliminary findings underlined the benefit of grape seed extracts valorization due to their health-promoting properties. |
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| Item Description: | 10.3390/ph13050097 1424-8247 |