Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy

Altered Levels of MicroRNA-9, -206, and -132 in Spinal Muscular Atrophy and Their Response to Antisense Oligonucleotide Therapy

The identification of noninvasive biomarkers to monitor the disease progression in spinal muscular atrophy (SMA) is becoming increasingly important. MicroRNAs (miRNAs) regulate gene expression and are implicated in the pathogenesis of neuromuscular diseases, including motor neuron degeneration. In t...

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Main Authors: Francesco Catapano (Author), Irina Zaharieva (Author), Mariacristina Scoto (Author), Elena Marrosu (Author), Jennifer Morgan (Author), Francesco Muntoni (Author), Haiyan Zhou (Author)
Format: Book
Published: Elsevier, 2016-01-01T00:00:00Z.
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