Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose

• Main Authors: An Aerts (Author), Bjorn Baselet (Author), Niels Belmans (Author), Emma Coninx (Author), Donna Lowe (Author), Ann Janssen (Author), Arlette Michaux (Author), Kevin Tabury (Author), Kenneth Raj (Author), Roel Quintens (Author), Mohammed A. Benotmane (Author), Sarah Baatout (Author), Pierre Sonveaux (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Purpose: Epidemiological data suggests an excess risk of cardiovascular disease (CVD) at low doses (0.05 and 0.1 Gy) of ionizing radiation (IR). Furthermore, the underlying biological and molecular mechanisms of radiation-induced CVD are still unclear. Because damage to the endotheliu...