Blockade of Leukotriene B4 Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer

• প্রধান লেখক: Aya Ihara (লেখক), Koichiro Wada (লেখক), Masato Yoneda (লেখক), Nobutaka Fujisawa (লেখক), Hirokazu Takahashi (লেখক), Atsushi Nakajima (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2007-01-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

We investigated whether leukotriene B4 (LTB4) and its signaling pathway play an important role in the progression of human colon cancer via a direct stimulation of cancer cell proliferation. Remarkable expression of LTB4 receptor 1 (BLT1) in human colon cancer tissues was detected by immunohistochem...