Blockade of Leukotriene B4 Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer

• मुख्य लेखकों: Aya Ihara (लेखक), Koichiro Wada (लेखक), Masato Yoneda (लेखक), Nobutaka Fujisawa (लेखक), Hirokazu Takahashi (लेखक), Atsushi Nakajima (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2007-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We investigated whether leukotriene B4 (LTB4) and its signaling pathway play an important role in the progression of human colon cancer via a direct stimulation of cancer cell proliferation. Remarkable expression of LTB4 receptor 1 (BLT1) in human colon cancer tissues was detected by immunohistochem...