Blockade of Leukotriene B4 Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer

• Váldodahkkit: Aya Ihara (Dahkki), Koichiro Wada (Dahkki), Masato Yoneda (Dahkki), Nobutaka Fujisawa (Dahkki), Hirokazu Takahashi (Dahkki), Atsushi Nakajima (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2007-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

We investigated whether leukotriene B4 (LTB4) and its signaling pathway play an important role in the progression of human colon cancer via a direct stimulation of cancer cell proliferation. Remarkable expression of LTB4 receptor 1 (BLT1) in human colon cancer tissues was detected by immunohistochem...