Blockade of Leukotriene B4 Signaling Pathway Induces Apoptosis and Suppresses Cell Proliferation in Colon Cancer

• Asıl Yazarlar: Aya Ihara (Yazar), Koichiro Wada (Yazar), Masato Yoneda (Yazar), Nobutaka Fujisawa (Yazar), Hirokazu Takahashi (Yazar), Atsushi Nakajima (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2007-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We investigated whether leukotriene B4 (LTB4) and its signaling pathway play an important role in the progression of human colon cancer via a direct stimulation of cancer cell proliferation. Remarkable expression of LTB4 receptor 1 (BLT1) in human colon cancer tissues was detected by immunohistochem...