Synthesis, Antiproliferative Effect and In Silico LogP Prediction of BIM-23052 Analogs Containing Tyr Instead of Phe

Synthesis, Antiproliferative Effect and In Silico LogP Prediction of BIM-23052 Analogs Containing Tyr Instead of Phe

(1) Background: Hydrophobicity (or lipophilicity) is a limiting factor in the ability of molecules to pass through cell membranes and to perform their function. The ability to efficiently access cytosol is especially important when a synthetic compound has the potential to become a drug substance. D...

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Main Authors: Dancho Danalev (Author), Ivan Iliev (Author), Stefan Dobrev (Author), Silvia Angelova (Author), Stoiko Petrin (Author), Tatyana Dzimbova (Author), Elena Ivanova (Author), Dessislava Borisova (Author), Emilia Naydenova (Author)
Format: Book
Published: MDPI AG, 2023-03-01T00:00:00Z.
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3rd Floor Main Library

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