Dipeptidyl Peptidase IV Inhibitor MK-0626 Attenuates Pancreatic Islet Injury in Tacrolimus-Induced Diabetic Rats

• Main Authors: Sun Woo Lim (Author), Jin Long (Author), Doh Kyoung Chan (Author), Jin Jian (Author), Piao Shang Guo (Author), Chung Byung Ha (Author), Yang Chul Woo (Author)
• Format: Book
• Published: The Korean Society of Nephrology, 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tacrolimus (TAC)-induced pancreatic islet injury is one of the important causes of new onset of diabetes in transplant recipients. This study was performed to evaluate whether a dipeptidyl peptidase (DPP) IV inhibitor is effective in improving TAC-induced diabetes mellitus by reducing pancreatic isl...