Fe Porphyrin-Based SOD Mimic and Redox-Active Compound, (OH)FeTnHex-2-PyP⁴⁺, in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue, (H₂O)MnTnHex-2-PyP⁵⁺

• Main Authors: Litao Li (Author), Artak Tovmasyan (Author), Huaxin Sheng (Author), Bin Xu (Author), Romulo S. Sampaio (Author), Julio S. Reboucas (Author), David S. Warner (Author), Ines Batinic-Haberle (Author), Ivan Spasojevic (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mn(III) <i>meso</i>-tetrakis(<i>N</i>-n-hexylpyridinium-2-yl)porphyrin, (H₂O)MnTnHex-2-PyP⁵⁺ (MnHex) carrying long hexyl chains, is a lipophilic mimic of superoxide dismutase (SOD) and a redox-active drug candidate. MnHex crosses...