Enhanced Bioavailability and Efficacy of Silymarin Solid Dispersion in Rats with Acetaminophen-Induced Hepatotoxicity

We evaluated the bioavailability, liver distribution, and efficacy of silymarin-D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) solid dispersion (silymarin-SD) in rats with acetaminophen-induced hepatotoxicity (APAP) compared with silymarin alone. The solubility of silybin, the major and ac...

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Main Authors: Im-Sook Song (Author), So-Jeong Nam (Author), Ji-Hyeon Jeon (Author), Soo-Jin Park (Author), Min-Koo Choi (Author)
Format: Book
Published: MDPI AG, 2021-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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