Deciphering the mechanism of Tinospora cordifolia extract on Th17 cells through in-depth transcriptomic profiling and in silico analysis

• Main Authors: Amrita Nandan (Author), Vishwas Sharma (Author), Prodyot Banerjee (Author), Kannan Sadasivam (Author), Subramanian Venkatesan (Author), Bhavana Prasher (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Naive CD4+ T cells differentiate into effector (Th1, Th2, Th17) cells and immunosuppressive (Treg) cells upon antigenic stimulation in the presence of a specific cytokine milieu. The T cell in vitro culture system provides a very efficient model to study compounds' therapeutic activity and mech...