Interleukin-13 promotes cellular senescence through inducing mitochondrial dysfunction in IgG4-related sialadenitis

• Main Authors: Mengqi Zhu (Author), Sainan Min (Author), Xiangdi Mao (Author), Yuan Zhou (Author), Yan Zhang (Author), Wei Li (Author), Li Li (Author), Liling Wu (Author), Xin Cong (Author), Guangyan Yu (Author)
• Format: Book
• Published: Nature Publishing Group, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Immunoglobulin G4-related sialadenitis (IgG4-RS) is an immune-mediated fibro-inflammatory disease and the pathogenesis is still not fully understood. The aim of this study was to explore the role and mechanism of interleukin-13 (IL-13) in the cellular senescence during the progress of IgG4-...