The Complex Relationship between Diabetic Retinopathy and High-Mobility Group Box: A Review of Molecular Pathways and Therapeutic Strategies

• Glavni autori: Marcella Nebbioso (Autor), Alessandro Lambiase (Autor), Marta Armentano (Autor), Giosuè Tucciarone (Autor), Vincenza Bonfiglio (Autor), Rocco Plateroti (Autor), Ludovico Alisi (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2020-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

High-mobility group box 1 (HMGB1) is a protein that is part of a larger family of non-histone nuclear proteins. HMGB1 is a ubiquitary protein with different isoforms, linked to numerous physiological and pathological pathways. HMGB1 is involved in cytokine and chemokine release, leukocyte activation...