The Complex Relationship between Diabetic Retinopathy and High-Mobility Group Box: A Review of Molecular Pathways and Therapeutic Strategies

• Hauptverfasser: Marcella Nebbioso (Verfasst von), Alessandro Lambiase (Verfasst von), Marta Armentano (Verfasst von), Giosuè Tucciarone (Verfasst von), Vincenza Bonfiglio (Verfasst von), Rocco Plateroti (Verfasst von), Ludovico Alisi (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2020-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

High-mobility group box 1 (HMGB1) is a protein that is part of a larger family of non-histone nuclear proteins. HMGB1 is a ubiquitary protein with different isoforms, linked to numerous physiological and pathological pathways. HMGB1 is involved in cytokine and chemokine release, leukocyte activation...