Targeting the gram-negative bacteria peptidoglycan synthase MraY as a new approach for monoclonal antibody anti-bacterial activity

• Autors principals: Jun Cao (Autor), Fei Yi (Autor), Qiufeng Tian (Autor), Guanghui Dang (Autor), Wei Si (Autor), Siguo Liu (Autor), Shenye Yu (Autor)
• Format: Llibre
• Publicat: Taylor & Francis Group, 2017-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The use of antibiotics to target bacteria is a well-validated approach for controlling infections in animals and humans. Peptidoglycan biosynthesis is a crucial process in bacteria, and the conserved peptidoglycan synthase MraY is an attractive target for drug design. However, due to the lack of det...