Impaired proteostatic mechanisms other than decreased protein synthesis limit old skeletal muscle recovery after disuse atrophy

• Main Authors: Jordan D. Fuqua (Author), Marcus M. Lawrence (Author), Zachary R. Hettinger (Author), Agnieszka K. Borowik (Author), Parker L. Brecheen (Author), Marcelina M. Szczygiel (Author), Claire B. Abbott (Author), Frederick F. Peelor III (Author), Amy L. Confides (Author), Michael Kinter (Author), Sue C. Bodine (Author), Esther E. Dupont‐Versteegden (Author), Benjamin F. Miller (Author)
• Format: Book
• Published: Wiley, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skeletal muscle mass and strength diminish during periods of disuse but recover upon return to weight bearing in healthy adults but are incomplete in old muscle. Efforts to improve muscle recovery in older individuals commonly aim at increasing myofibrillar protein synthesis via...