Decreased serum DNase1-activity in patients with autoimmune liver diseases

• المؤلفون الرئيسيون: Nikolaos K. Gatselis (مؤلف), Aigli G. Vakrakou (مؤلف), Kalliopi Zachou (مؤلف), Theodoros Androutsakos (مؤلف), Kalliopi Azariadis (مؤلف), Gregorios Hatzis (مؤلف), Menelaos N. Manoussakis (مؤلف), George N. Dalekos (مؤلف)
• التنسيق: كتاب
• منشور في: Taylor & Francis Group, 2017-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Deoxyribonuclease1 (DNase1) is involved in chromatin degradation of apoptotic cells. Its deficiency results in accumulation of self-DNA, which in turn may induce inflammation and autoimmunity. We assessed for the first time serum DNase1-activity in a large consecutive cohort of treatment-naïve pati...