Effect of high dose vitamin D3 on the HIV-1 reservoir: A pilot randomised controlled trial

• Main Authors: Matthew C. Pitman (Author), Niamh Meagher (Author), David J. Price (Author), Ajantha Rhodes (Author), J. Judy Chang (Author), Barbara Scher (Author), Brent Allan (Author), Alan Street (Author), James H. McMahon (Author), Thomas A. Rasmussen (Author), Paul U. Cameron (Author), Jennifer F. Hoy (Author), Stephen J. Kent (Author), Sharon R. Lewin (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Antiretroviral therapy for people living with HIV-1 must be taken lifelong due to the persistence of latent virus in long-lived and proliferating CD4+ T cells. Vitamin D3 is a steroidal gene transcription regulator which exerts diverse effects on immune and epithelial cells including r...