Tirbanibulin Attenuates Pulmonary Fibrosis by Modulating Src/STAT3 Signaling

• Main Authors: Xin Wang (Author), Rui Ren (Author), Zehui Xu (Author), Haidi Huang (Author), Wanglin Jiang (Author), Jinbo Ma (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tirbanibulin (KX-01) is the first clinical Src inhibitor of the novel peptidomimetic class that targets the peptide substrate site of Src providing more specificity toward the Src kinase. This study assessed the impact of KX-01 on cobalt chloride (CoCl2)-treated L929 cells and bleomycin (BLM)-induce...