Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H<sub>2</sub>O<sub>2</sub>- and Aβ<sub>1-42</sub>-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells

Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H<sub>2</sub>O<sub>2</sub>- and Aβ<sub>1-42</sub>-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells

With the lack of available drugs able to prevent the progression of Alzheimer’s disease (AD), the discovery of new neuroprotective treatments able to rescue neurons from cell injury is presently a matter of extreme importance and urgency. Here, we were inspired by the widely reported potential of na...

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Main Authors: Ana M. de Matos (Author), Alice Martins (Author), Teresa Man (Author), David Evans (Author), Magnus Walter (Author), Maria Conceição Oliveira (Author), Óscar López (Author), José G. Fernandez-Bolaños (Author), Philipp Dätwyler (Author), Beat Ernst (Author), M. Paula Macedo (Author), Marialessandra Contino (Author), Nicola A. Colabufo (Author), Amélia P. Rauter (Author)
Format: Book
Published: MDPI AG, 2019-06-01T00:00:00Z.
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