Pharmacophore-based design and discovery of (−)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis
Multifunctional carbamate-type acetylcholinesterase (AChE) inhibitors with anti-amyloidogenic properties like phenserine are potential therapeutic agents for Alzheimer's disease (AD). We reported here the design of new carbamates using pharmacophore model strategy to modulate both cholinesteras...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Taylor & Francis Group,
2017-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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