Improving the Virtual Screening Ability of Target-Specific Scoring Functions Using Deep Learning Methods

• Main Authors: Dingyan Wang (Author), Chen Cui (Author), Xiaoyu Ding (Author), Zhaoping Xiong (Author), Mingyue Zheng (Author), Xiaomin Luo (Author), Hualiang Jiang (Author), Kaixian Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Scoring functions play an important role in structure-based virtual screening. It has been widely accepted that target-specific scoring functions (TSSFs) may achieve better performance compared with universal scoring functions in actual drug research and development processes. A method that can effe...