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Morphological Change by Overexpression of D385A Dominant Negative Presenilin 1 in Human Neuroblastoma SH-SY5Y Cells

Presenilin 1 (PS1) is a multifunctional protein, and its mutations are highly related to familial Alzheimer's disease (AD). In this study, we examined the effects of PS1 overexpression on neuronal morphology using SH-SY5Y cells. Overexpression of dominant-negative D385A PS1 induced morphologica...

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Main Authors:	Daiju Tsuchiya (Author), Yoshihisa Kitamura (Author), Kazuyuki Takata (Author), Takashi Taniguchi (Author), Kengo Uemura (Author), Hiroaki Miki (Author), Tadaomi Takenawa (Author), Shun Shimohama (Author)
Format:	Book
Published:	Elsevier, 2006-01-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
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