Development and validation of an LC-MS/MS method for simultaneous quantification of co-administered trastuzumab and pertuzumab

• Asıl Yazarlar: Sandor Schokker (Yazar), Fabrizia Fusetti (Yazar), Francesco Bonardi (Yazar), Remco J. Molenaar (Yazar), Ron A.A. Mathôt (Yazar), Hanneke W.M. van Laarhoven (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Given the increasing use of combination therapy with multiple monoclonal antibodies (mAbs), there is a clinical need for multiplexing assays. For the frequently co-administered anti-human epidermal growth factor receptor 2 (HER2) mAbs trastuzumab and pertuzumab, we developed a high-throughput and ro...