Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression

• Main Authors: Eveline Bruinstroop (Author), Jin Zhou (Author), Madhulika Tripathi (Author), Winifred W. Yau (Author), Anita Boelen (Author), Brijesh Kumar Singh (Author), Paul M. Yen (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T4) have a higher incidence of NAFLD, and thyroid hormone treatment is very pr...