An optimized MNK1b aptamer, apMNKQ2, and its potential use as a therapeutic agent in breast cancer

• Main Authors: C. Pinto-Díez (Author), R. Ferreras-Martín (Author), R. Carrión-Marchante (Author), J.I. Klett-Mingo (Author), M. García-Hernández (Author), M.I. Pérez-Morgado (Author), S. Sacristán (Author), M. Barragán (Author), M. Seijo-Vila (Author), I. Tundidor (Author), S. Blasco-Benito (Author), E. Pérez-Gómez (Author), I. Gómez-Pinto (Author), C. Sánchez (Author), C. González (Author), V.M. González (Author), M.E. Martín (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Breast cancer is the most commonly diagnosed and leading cause of cancer death among women worldwide. Mitogen-activated protein kinase-interacting kinases (MNKs) promote the expression of several oncogenic proteins and are overexpressed in several types of cancer. In human cells, there are four isof...