Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma.

• Main Authors: Wilson Lim (Author), Bertrand Nyuykonge (Author), Kimberly Eadie (Author), Mickey Konings (Author), Juli Smeets (Author), Ahmed Fahal (Author), Alexandro Bonifaz (Author), Matthew Todd (Author), Benjamin Perry (Author), Kirandeep Samby (Author), Jeremy Burrows (Author), Annelies Verbon (Author), Wendy van de Sande (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Eumycetoma is a chronic subcutaneous neglected tropical disease that can be caused by more than 40 different fungal causative agents. The most common causative agents produce black grains and belong to the fungal orders Sordariales and Pleosporales. The current antifungal agents used to treat eumyce...