Directed evaluation of enterotoxigenic Escherichia coli autotransporter proteins as putative vaccine candidates.

• Main Authors: Jessica A Harris (Author), Koushik Roy (Author), Virginia Woo-Rasberry (Author), David J Hamilton (Author), Rita Kansal (Author), Firdausi Qadri (Author), James M Fleckenstein (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Enterotoxigenic Escherichia coli (ETEC) is a major diarrheal pathogen in developing countries, where it accounts for millions of infections and hundreds of thousands of deaths annually. While vaccine development to prevent diarrheal illness due to ETEC is feasible, extensive effort is needed to iden...