Bioanalytical method validation for therapeutic drug monitoring of olaparib in patients with ovarian cancer

• Những tác giả chính: Konrad Lewandowski (Tác giả), Agnieszka Karbownik (Tác giả), Andrzej Czyrski (Tác giả), Hanna Urjasz (Tác giả), Joanna Stanisławiak-Rudowicz (Tác giả), Edmund Grześkowiak (Tác giả), Edyta Szałek (Tác giả)
• Định dạng: Sách
• Được phát hành: Polskie Towarzystwo Farmaceutyczne, 2024-06-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Olaparib, an oral poly-ADP ribose polymerase (PARP) inhibitor, is a relatively new anticancer drug. It is essential to find TDM-guided dosage for better safety and tolerability of patients. However, first, it is important to develop a suitable analytical method to conduct reliable TDM. The aim of th...