Bioanalytical method validation for therapeutic drug monitoring of olaparib in patients with ovarian cancer

• Main Authors: Konrad Lewandowski (Author), Agnieszka Karbownik (Author), Andrzej Czyrski (Author), Hanna Urjasz (Author), Joanna Stanisławiak-Rudowicz (Author), Edmund Grześkowiak (Author), Edyta Szałek (Author)
• Format: Book
• Published: Polskie Towarzystwo Farmaceutyczne, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Olaparib, an oral poly-ADP ribose polymerase (PARP) inhibitor, is a relatively new anticancer drug. It is essential to find TDM-guided dosage for better safety and tolerability of patients. However, first, it is important to develop a suitable analytical method to conduct reliable TDM. The aim of th...