Establishment and Characterization of Mammalian Cell Lines Stably Expressing Human l-Type Amino Acid Transporters

• Main Authors: Emiko Morimoto (Author), Yoshikatsu Kanai (Author), Do Kyung Kim (Author), Arthit Chairoungdua (Author), Hye Won Choi (Author), Michael F. Wempe (Author), Naohiko Anzai (Author), Hitoshi Endou (Author)
• Format: Book
• Published: Elsevier, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

System L (SL), a basolateral amino acid transporter, transports large neutral amino acids (LNAAs) in a Na+-independent manner. Previously, we identified two isoforms of transporters: l-type amino acid transporter 1 (LAT1) and 2 (LAT2) and revealed their distinct substrate selectivity and transport p...