Association of mitochondrial deoxyribonucleic acid mutation with polymorphism in CYP2E1 gene in oral carcinogenesis

• Main Authors: Rahul Pandey (Author), Divya Mehrotra (Author), Carlo Catapano (Author), Vimal Choubey (Author), Rajiv Sarin (Author), Abbas Ali Mahdi (Author), Stuti Singh (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT: Background: Oral carcinogenesis is a complex process affected by genetic as well as environmental factors. CYP2E1 gene is involved in metabolism of number of compounds and carcinogens. Its normal functioning is required for homeostasis of free radical. Mitochondrial deoxyribonucleic acid (...