Topical GZ21T Inhibits the Growth of Actinic Keratoses in a UVB-Induced Model of Skin Carcinogenesis

• Main Authors: Zachary A. Bordeaux (Author), Justin Choi (Author), Gabriella Braun (Author), Cole Davis (Author), Melika Marani (Author), Kevin Lee (Author), Christeen Samuel (Author), Jackson Adams (Author), Reed Windom (Author), Anthony Pollizzi (Author), Anusha Kambala (Author), Hannah Cornman (Author), Sriya V. Reddy (Author), Weiying Lu (Author), Olusola O. Oladipo (Author), Martin P. Alphonse (Author), Cameron E. West (Author), Shawn G. Kwatra (Author), Madan M. Kwatra (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Actinic keratoses (AKs) are premalignant intraepidermal neoplasms that occur as a result of cumulative sun damage. AKs commonly relapse, and up to 16% undergo malignant transformation into cutaneous squamous cell carcinoma. There is a need for novel therapies that reduce the quantity and surface are...