Pharmacokinetic-Pharmacodynamic Correlation Analysis of <i>Rhodiola crenulata</i> in Rats with Myocardial Ischemia

• Main Authors: Zhixin Jia (Author), Guoming Zou (Author), Yongyan Xie (Author), Enning Zhang (Author), Mureziya Yimingjiang (Author), Xianlong Cheng (Author), Cong Fang (Author), Feng Wei (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pharmacokinetics (PK) of <i>Rhodiola crenulata</i> in rats were studied, and pharmacokinetic-pharmacodynamic (PK-PD) correlation analysis was performed to elucidate their time-concentration-effect relationship. The myocardial ischemia model was made with pituitrin. Rats were divided...