The Severity of Visceral Leishmaniasis Correlates with Elevated Levels of Serum IL-6, IL-27 and sCD14.

• Main Authors: Priscila L Dos Santos (Author), Fabrícia A de Oliveira (Author), Micheli Luize B Santos (Author), Luana Celina S Cunha (Author), Michelle T B Lino (Author), Michelle F S de Oliveira (Author), Manuela O M Bomfim (Author), Angela Maria Silva (Author), Tatiana R de Moura (Author), Amélia R de Jesus (Author), Malcolm S Duthie (Author), Steven G Reed (Author), Roque P de Almeida (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Visceral leishmaniasis (VL) is a severe disease caused by infection with protozoa of the genus Leishmania. Classic VL is characterized by a systemic infection of phagocytic cells and an intense activation of the inflammatory response. It is unclear why 90% of infected individuals do not d...