Exploring the MIR143-UPAR Axis for the Inhibition of Human Prostate Cancer Cells In Vitro and In Vivo

• Main Authors: Sven Wach (Author), Madeleine Brandl (Author), Hannes Borchardt (Author), Katrin Weigelt (Author), Sabine Lukat (Author), Elke Nolte (Author), Omar Al-Janabi (Author), Martin Hart (Author), Friedrich Grässer (Author), Johannes Giedl (Author), Rudolf Jung (Author), Robert Stöhr (Author), Arndt Hartmann (Author), Verena Lieb (Author), Sabrina Höbel (Author), Anna Peters (Author), Claudia Stäubert (Author), Bernd Wullich (Author), Helge Taubert (Author), Achim Aigner (Author)
• Format: Bog
• Udgivet: Elsevier, 2019-06-01T00:00:00Z.
• Fag: article
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MIR143 is pathologically downregulated and may function as a tumor suppressor in prostate cancer. Likewise, the urokinase plasminogen activator receptor (UPAR) is overexpressed in prostate carcinoma, representing a negative prognostic marker and putative therapeutic target gene. In this paper, we es...