Cross-reactivity of antibodies against leptospiral recurrent uveitis-associated proteins A and B (LruA and LruB) with eye proteins.

• Main Authors: Ashutosh Verma (Author), Pawan Kumar (Author), Kelly Babb (Author), John F Timoney (Author), Brian Stevenson (Author)
• פורמט: ספר
• יצא לאור: Public Library of Science (PLoS), 2010-08-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Infection by Leptospira interrogans has been causally associated with human and equine uveitis. Studies in our laboratories have demonstrated that leptospiral lipoprotein LruA and LruB are expressed in the eyes of uveitic horses, and that antibodies directed against LruA and LruB react with equine l...